Future-proofing Cambridge's science cluster in a fast-moving R&D economy

07.1.26

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Cambridge’s longevity as a science cluster provides a marker in how other science and tech bases economies in the UK will need to evolve to accommodate structural redefinition driven by the convergence of science and technology.

Cambridge is the UK’s most mature life sciences cluster, yet the scale of transformation over the past decade has been remarkable even by its own historic standards. The city now anchors one of the world’s most advanced knowledge economies - second only to Silicon Valley for innovation output on a per-capita basis, according to the World Intellectual Property Organisation’s 2025 ranking. This evolution has had significant implications for the structure of employment, the demands on business space, and the future requirements of scientific infrastructure.

Across the Oxford–Cambridge Corridor, Knowledge Intensive (KI) industries—spanning IT and telecommunications, advanced manufacturing, life sciences, and engineering consultancy—constitute a distinctive share of economic activity. KI industries represent 29% of employment within the Corridor, almost three times the average for Great Britain (11%), reflecting the density of globally competitive universities, research institutes and clinical centres.

Cambridge’s trajectory, however, has been more pronounced. Today, 37% of all employment is situated within KI sectors (Bidwells, CBR, Nomis 2025). This shift is not merely proportional; it signals the rapid expansion of high-value sectors that have outpaced the growth of the wider economy. Correspondingly, the profile of businesses occupying the city’s commercial space has undergone a notable restructuring. Approximately 88% of floorspace across the city’s science parks and innovation districts is now used by KI occupiers, and half taken by life sciences companies (Bidwells, 2025). This has been attained by the steady increase in lettings to KI companies over the last decade

This is a pattern that continued in 2025 and we expect to be reflected in the market trends we report in our H2 Databook reports over the next couple of weeks.

Source: Bidwells Research, 2026

The stability in the ratio of science and technology floorspace, despite the addition of 1.5 million sq ft of new space over the past five years, reflects the evolving interdependence between science and technology. 

This is seen in the expansion of AI, robotics, and data-intensive research, but Cambridge has also seen the proportion of business space occupied by advanced engineering company grow double since 2019.

Cambridge’s employment and spatial structures are therefore increasingly characterised by a dominance of scientific, engineering, and computational activities rather than traditional office-based service industries. However, while Cambridge is often characterised primarily as a laboratory market, its office sector is undergoing a parallel structural realignment towards technology. In mid-2025, technology occupiers accounted for approximately half of all office requirements by floorspace, while life sciences and healthcare firms also formed a further substantial share. The longer-term direction of travel points toward an office market increasingly shaped by hybrid science-technology occupiers.

These advances have continued despite a demanding financial backdrop. While late-stage funding for life sciences in Cambridge remains relatively resilient, early-stage VC investment has moderated from its pandemic-era peak, a challenge for a city which is a hot bed of university and research-institute spinouts. Positively, technology funding is improving, with a marked increase in tech VC investment in Q3 2025 expected to underpin a strong annual outturn. This shift underscores the maturation of a broader deep-tech ecosystem encompassing AI, quantum technologies, advanced engineering, and computational science.

Certainly, advances in artificial intelligence are reshaping scientific discovery, from drug-target identification to protein design and predictive modelling. This is transforming the spatial and technical requirements of research-oriented businesses. Laboratories now require greater automation capability, more robust digital infrastructure, and in some cases closer adjacency to computational teams. Offices, in turn, are becoming integral to R&D activity whether combined with lab activities or co-located nearby space, facilitating interdisciplinary collaboration across biology, engineering, computer science, and data analysis.

The implication is clear: future business space in Cambridge, whether laboratory, office, or hybrid R&D, must be designed with significantly greater flexibility and higher technical capacity. Features likely to become essential include integrated/expanded computational areas, increased power and cooling infrastructure, and reconfigurable lab layouts. Allowing for enhanced computing power and greater collaboration between wet-lab researchers and data scientists.

Cambridge’s longevity as a science cluster provides a marker in how other science and tech bases economies in the UK will need to evolve to accommodate structural redefinition driven by the convergence of science and technology.

As advances reshape the nature of discovery, business space must evolve accordingly, ensuring that new and existing assets remain sufficiently adaptable to accommodate the next generation of scientific and technological breakthroughs.

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Simon Green

Simon Green

Partner, Project Management

Simon is commercially aware with excellent interpersonal and team management skills and is a competent contract administrator.

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